Heteromeric GABAA receptor structures in positively-modulated active states
Paul S. Miller, Simonas Masiulis, Tomas Malinauskas, Abhay Kotecha, Shanlin Rao, Sreenivas Chavali, Luigi De Colibus, Els Pardon, Saad Hannan, Suzanne Scott, Zhaoyang Sun, Brandon Frenz, Gianni Klesse, Sai Li, Jonathan M. Diprose, , A. Radu Aricescu
The paper reports cryo-EM and crystal structures of GABAA receptors with ligands, revealing the molecular basis of BZD modulation.
bioRxiv · Jun 5, 2018 · PreprintBiophysics