MmCMS: Mouse models' Consensus Molecular Subtypes of colorectal cancer
R. Amirkhah, K. Gilroy, S. Malla, T. Lannagan, R. Byrne, N. C. Fisher, S. Corry, H. Naderi-Meshkin, B. Ahmaderaghi, R. Murray, M. Mills, A. Campbell, ACRCelerate consortium, A. Berenguer Llergo, R. Sanz-Pamplona, , P. Dunne
The paper develops three methods to classify mouse colorectal cancer models into human CMS subtypes, finding that pathway-level classifiers outperform gene-level ones for accurate subtype identification.
bioRxiv · Jun 17, 2022Cancer Biology