The microbial soy metabolite S-equol mitigates cadmium neurotoxicity in mice
Youjun Suh, Hao Wang, Lingjun Li, Haiwei Gu, Johannes P. Johnson-Martínez, Adrew Magis, Sean M. Gibbons, Julia Yue Cui
This study shows that S-equol, a microbial metabolite, reduces cadmium-induced neurotoxicity in mice by restoring neural gene expression and is associated with lower levels in humans carrying the apolipoprotein E4 allele.
bioRxiv · Oct 6, 2026 · PreprintNeuroscience