Author

Alec Dick

Boehringer Ingelheim (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Molecular Biology· 1 Pharmacology & Toxicology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Approach:statistical model· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Diana Santacruz· 3 shared Fidel RamíreziD· 3 shared Benjamin StrobeliD· 2 shared Christoph H. MayriD· 2 shared Coralie ViolletiD· 2 shared Matthew James ThomasiD· 2 shared Werner Rust· 2 shared Alexander BarteltiD· 1 shared

Activity by Year

2023-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Diana Santacruz

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The obesity-linked peptide SP16 regulates adipocytes through GIP and insulin receptor

Thi My Hanh Ngo, Rakesh Santhanam, Daniel P. Teufel, Alec Dick, Daniel Lam, Holger Klein, Andreas‐David Brunner, Mafalda Maria Azevedo Pereira, Alexander Bartelt, Anton Pekcec, Maude Giroud

This study identifies SP16 as a novel GIP receptor agonist that promotes lipolysis and has metabolic benefits in diet-induced obese mice.

bioRxiv · Jun 17, 2025 · PreprintPharmacology & Toxicology

AXL-GAS6/PROS1 Interaction: A Critical Switch Between Aberrant- and Healthy Repair Following Alveolar Lung Injury

Devona Soetopo, Christoph H. Mayr, Katrin Fundel‐Clemens, Fidel Ramírez, Coralie Viollet, Alec Dick, Werner Rust, Diana Santacruz, Yvette Hoevels, Christopher J. Applebee, Sam Legg, Anastasia Funk, Gisela Schnapp, Julian A. Padget, Benjamin Strobel, , Kerstin Geillinger-Kästle

This study investigates ligand-specific AXL signaling in IPF, showing GAS6 promotes basal cell proliferation while PROS1 inhibits it, with implications for therapeutic targets.

bioRxiv · Apr 7, 2025 · PreprintMolecular Biology

JUNB O-GlcNAcylation-mediated promoter accessibility of metabolic genes modulates distinct epithelial lineage in pulmonary fibrosis

Marie‐Therese Bammert, Meshal Ansari, Leoni Haag, Zuhdi Ahmad, Victoria Schröder, Joseph Birch, Diana Santacruz, Werner Rust, Coralie Viollet, Benjamin Strobel, Alec Dick, Florian Gantner, Holger Schlüter, Fidel Ramírez, Muriel Lizé, , Huy Quang Le

The paper identifies O-GlcNAcylation of JUNB as a regulator of promoter accessibility in metabolic genes, driving aberrant epithelial lineage in IPF.

Advanced Science · Dec 15, 2024Peer-reviewedCell Biology

Spatial Transcriptomic Characterization of Novel Pathologic Niches in IPF

Christoph H. Mayr, Diana Santacruz, Sebastian Jarosch, Charlotte Lempp, Lavinia Neubert, Berenice Rath, Jan C. Kamp, Danny David Jonigk, Mark Kühnel, Holger Schlueter, Jonas Doerr, Alec Dick, Fidel Ramírez, Matthew James Thomas

The paper uses spatial transcriptomics to identify novel pathologic niches in IPF lung tissue and their cellular composition and communication.

bioRxiv · Dec 13, 2023 · PreprintSystems Biology