Author
Boehringer Ingelheim (Germany)ORCID 0000-0002-1529-0130Unclaimed ORCID profile · follow to get notified of new preprints
3 papers
Recent·Most cited
Devona Soetopo, Christoph H. Mayr, Katrin Fundel‐Clemens…·Kerstin Geillinger-Kästle
This study investigates ligand-specific AXL signaling in IPF, showing GAS6 promotes basal cell proliferation while PROS1 inhibits it, with implications for therapeutic targets.
Vera Hedwig, Maike Spöring, Gary E. Aspnes…·Oliver Hucke
The paper designs a drug-like small molecule modulator of a custom riboswitch, achieving high affinity and orthogonality for gene expression control in human cells.
Tomas C. Pascoa, Ashley C. W. Pike, Christofer S. Tautermann…·David Bryant Sauer
This study determines the structural mechanism of CerS6, a ceramide synthase, using cryo-EM and biochemical analysis, revealing a ping-pong reaction mechanism and insights into fumonisin B1 inhibition.