Author

Alexis Moreau

Yale UniversityPrimary ORCID profile (0000-0002-0559-6179 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Same name, identified by ORCID

Alexis MoreauiD1 paper · Yale University

Biology Disciplines

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Biophysics· 2 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:statistical model· 2 Approach:biophysical modeling· 1 Research Focus:cell-cell communication· 1 Research Focus:clustering· 1

Frequent Co-Authors

Jing Quan YaniD· 3 shared Rich OlsoniD· 3 shared Alexander J. Hinbest· 2 shared Emma Gerace· 2 shared Nathan Fowler· 2 shared Rajan KandeliD· 2 shared Ranjuna WeerasekeraiD· 2 shared Anthony Zamora· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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3 shared papersBiophysics

Jing Quan YanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Structure of a key adhesin-exopolysaccharide interaction provides insights into matrix assembly in Vibrio cholerae biofilms

Alexander J. Hinbest, Hyerim Bianca Nam, Ewelina D. Liszczyk, Rajan Kandel, Emma Gerace, Alexis Moreau, Ranjuna Weerasekera, Ryan Gordon, Yiyan Yang, Jack Chen, Nathan Fowler, Xiaofang Jiang, Robert J. Woods, Jing Quan Yan, Rich Olson

This study determines the structure of Bap1 bound to VPS and shows how it facilitates biofilm adhesion and VPS organization through a conserved β-propeller interaction.

bioRxiv · Aug 4, 2026 · PreprintMicrobiology

Conformational dynamics of exopolysaccharides underlie biofilm matrix mechanics in Vibrio cholerae

Kee-Myoung Nam, Nathan Fowler, Rajan Kandel, Yongqi Zhu, Yuchu Liu, Yi-Jhen Lai, Muhammad Faheem Hassan, Emma Gerace, Merrill E. Asp, Rich Olson, Ying Li, Mu‐Ping Nieh, Mingjiang Zhong, Robert J. Woods, Alexis Moreau, Jing Quan Yan

This study characterizes the physical properties and conformational dynamics of Vibrio cholerae exopolysaccharides to understand their role in biofilm matrix mechanics.

bioRxiv · Jul 23, 2026 · PreprintBiophysics

Surface remodeling and inversion of cell-matrix interactions underlies community recognition and dispersal in Vibrio cholerae biofilms

Alexis Moreau, Dang H. Nguyen, Alexander J. Hinbest, Anthony Zamora, Ranjuna Weerasekera, Katherine Matej, Xuening Zhou, Sandra Sánchez, Ignacio A. Rodriguez-Brenes, Jung‐Shen B. Tai, Carey D. Nadell, Wai‐Leung Ng, Vernita Diane Gordon, Natalia L. Komarova, Rich Olson, , Jing Quan Yan

This study shows that Vibrio cholerae biofilms undergo surface remodeling and inversion of cell-matrix interactions, shifting from attractive to repulsive as biofilms age, which facilitates dispersal.

Nature Communications · Jan 2, 2025Peer-reviewedBiophysics