Molecular BiologybioRxivPreprint
Generation of C9orf72h370 mice, an intron 1 humanised C9orf72 repeat-expansion knock-in model
R. Nair, Mireia Carcolé, David Thompson…·Thomas J. Cunningham
The paper generates a mouse model with a humanised C9orf72 repeat expansion to study ALS and FTD, and demonstrates a method for creating such repeat expansions in genomic sequences.
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