Author

Andrew Moreno

Harvard University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2 Biophysics· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Joseph J. LoparoiD· 3 shared Patrick CalsouiD· 2 shared Philippe FritiD· 2 shared Sébastien BrittoniD· 2 shared Alan GilliD· 1 shared António PeixotoiD· 1 shared Benjamin M. StinsoniD· 1 shared Fernando G. VieiraiD· 1 shared

Activity by Year

2019-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMolecular Biology

Joseph J. LoparoORCID

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Author profile →

4 papers

Recent·Most cited

Sequential division of labor between PAXX and XLF drives NHEJ synaptic complex stability and maturation

Jinghang Zhang, Philippe Frit, Andrew Moreno, Nadia Barboule, Patrick Calsou, Sébastien Britton, Joseph J. Loparo

The paper shows PAXX and XLF have sequential roles in stabilizing and maturing the NHEJ synaptic complex through distinct interactions.

bioRxiv · Aug 12, 2026 · PreprintBiophysics

Identification of the main barriers to Ku accumulation in chromatin

Madeleine Bossaert, Andrew Moreno, António Peixoto, Marie‐Jeanne Pillaire, Pauline Chanut, Philippe Frit, Patrick Calsou, Joseph J. Loparo, Sébastien Britton

The paper identifies mechanisms that limit Ku protein accumulation in chromatin, showing DNA-PKcs blocks Ku entry, and two additional mechanisms restrict Ku levels in the absence of DNA-PKcs.

Cell Reports · Jul 26, 2024Peer-reviewedMolecular Biology

PERK modulation, with GSK2606414, Sephin1 or salubrinal, failed to produce therapeutic benefits in the SOD1G93A mouse model of ALS

Fernando G. Vieira, Valerie R. Tassinari, Joshua D. Kidd, Andrew Moreno, Kenneth Thompson, Steven Perrin, Alan Gill, Theo Hatzipetros

This study evaluates three PERK modulators in an ALS mouse model and finds they do not provide therapeutic benefits, with some effects possibly mediated through PERK-independent mechanisms.

PLoS ONE · Feb 15, 2024Peer-reviewedNeuroscience

A mechanism to minimize errors during non-homologous end joining

Benjamin M. Stinson, Andrew Moreno, Johannes C. Walter, Joseph J. Loparo

This study reveals how NHEJ minimizes errors by confining end processing to a Lig4-dependent short-range synaptic complex, ensuring accurate DNA ligation.

Molecular Cell · Dec 17, 2019Peer-reviewedMolecular Biology