Author

Anna Melchert

Medizinische Hochschule Hannover

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:statistical model· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Colin DavenportiD· 1 shared Gudrun GöhringiD· 1 shared Ina GruhiD· 1 shared Jonas Gruber· 1 shared Kaja S. MengeiD· 1 shared Lutz Wiehlmann· 1 shared Maike KosankeiD· 1 shared Maike Sievert· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperGenomics

Colin DavenportORCID

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1 paper

Recent·Most cited

iPSC culture expansion selects against putatively actionable mutations in the mitochondrial genome

Maike Kosanke, Colin Davenport, Mónika Szepes, Lutz Wiehlmann, Tim Kohrn, Marie Dorda, Jonas Gruber, Kaja S. Menge, Maike Sievert, Anna Melchert, Ina Gruh, Gudrun Göhring, Ulrich Martin

The paper analyzes mtDNA variants in iPSCs and finds that culture expansion selects against harmful mitochondrial mutations, while reprogramming and differentiation do not significantly alter mtDNA heteroplasmy.

Stem Cell Reports · Sep 23, 2021Peer-reviewedGenomics