Endodermal BRD4 mediates epithelial-mesenchymal crosstalk during lung development
Derek C. Liberti, Hongbo Wen, Kwaku K. Quansah, Prashant Chandrasekaran, Josh Pankin, Sylvia N. Michki, Annabelle Jin, MinQi Lu, Maureen Peers de Nieuwburgh, Lisa R. Young, Rajan Jain, David B. Frank
This study shows that BRD4 in endodermal cells is crucial for lung development by facilitating epithelial-mesenchymal crosstalk, proper lineage allocation, and branching morphogenesis.
bioRxiv · May 21, 2023 · PreprintDevelopmental Biology