Dabigatran prevents lipopolysaccharide mediated apoptosis in zebrafish through a thrombin independent mechanism
Annelore Fleischmann, William Woodhams, Ritta Mouayed, Timmy Joseph, Xiangyu Sui, Murat Yaman, Stefan H. Oehlers, Jordan A. Shavit, Vinitha Jacob
This study identifies novel small molecules that prevent LPS-induced endotoxemia in zebrafish, showing that dabigatran protects through a thrombin-independent mechanism.
Shock · Jan 28, 2026Peer-reviewedPharmacology & Toxicology