Extended G2/M arrests lead to aberrant mitoses and cell death due to excessive securin
Anton Dubenko, Marah Jnied, Oleksii Kotenko, Svetlana Makovets
The paper shows that prolonged G2/M arrest due to DNA damage leads to aberrant mitoses and cell death via securin accumulation in yeast.
bioRxiv · Jul 21, 2025 · PreprintCell Biology