Reducing the CAV1-dependent trafficking of G6PC1 in the liver protects against the development of type 2 diabetes
Lorine Da Costa, Cécile Saint-Béat, Clara Bron, Arnaud Lang, Adeline Duchampt, Manon Micoud, Félicie Evrard, Gilles Mithieux, Amandine Gautier‐Stein
This study shows that reducing CAV1 in the liver decreases glucose production and improves metabolic parameters in diabetic mice.
bioRxiv · Apr 26, 2025 · PreprintPhysiology