NDUFA4L2 rescues hyperoxia-induced migration defects in retinal endothelial cells by reversing isocitrate dehydrogenase flux blockade
Hyungryun Jang, Ashwin Chandra, Kobe Tray, Brooke Linnehan, Fabian Schulte, Gopalan Gnanaguru, Charandeep Singh
The paper identifies NDUFA4L2 as a protein that rescues hyperoxia-induced migration defects in retinal endothelial cells by reversing isocitrate dehydrogenase flux blockade in a mouse model of oxygen-induced retinopathy.
bioRxiv · Jul 15, 2026 · PreprintBiochemistry