Author

Ayaka Hulbert

Fred Hutch Cancer Center

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Adam L. BurrackiD· 1 shared Alexander K. TsaiiD· 1 shared David MasopustiD· 1 shared Eduardo Cruz-HinojozaiD· 1 shared Grant H. HickokiD· 1 shared Guhan QianiD· 1 shared Hongrong ZhangiD· 1 shared Ingunn M. StromnesiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperImmunology

Adam L. BurrackORCID

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1 paper

Recent·Most cited

Abrogating TGFβ signaling in TCR-engineered T cells and enhancing antigen processing by tumor cells promotes sustained therapeutic activity in pancreatic ductal adenocarcinoma

Alexander K. Tsai, Meagan R. Rollins, Madeline A. Ellefson, Zoe C. Schmiechen, Adam L. Burrack, Ayaka Hulbert, Guhan Qian, Hongrong Zhang, Eduardo Cruz-Hinojoza, Jonah Z. Butler, Jason S. Mitchell, Olivia C. Ghirardelli Smith, Stephen D. O’Flanagan, Jenny Krause, Grant H. Hickok, , Ingunn M. Stromnes

This study shows that blocking TGFβ signaling in TCR-engineered T cells and enhancing antigen processing in tumor cells improves their therapeutic effectiveness against pancreatic ductal adenocarcinoma.

Journal for ImmunoTherapy of Cancer · Oct 1, 2026Peer-reviewedImmunology