Author

B. A. Lund

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Organism:bacteria (other)· 1 Research Focus:drug response / drug discovery· 1 Organism:E. coli· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

B. O. Brandsdal· 1 shared C. Frohlich· 1 shared G. V. Isaksen· 1 shared H.-K. S. Leiros· 1 shared J. A. Gama· 1 shared J. Aqvist· 1 shared K. Harms· 1 shared M. W. van der Kamp· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

B. O. Brandsdal

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Author profile →

2 papers

Recent·Most cited

Biophysical characterization and analysis of a mesophilic chorismate mutase from B. pumilus

R. S. Wilkins, B. A. Lund, G. V. Isaksen, J. Aqvist, B. O. Brandsdal

This study reports the first crystal structure and kinetic analysis of a mesophilic chorismate mutase from B. pumilus, using EVB/MD simulations to extract thermodynamic activation parameters.

bioRxiv · Apr 20, 2023 · PreprintBiochemistry

Cryptic β-lactamase evolution is driven by low β-lactam concentrations

C. Frohlich, J. A. Gama, K. Harms, V. H. A. Hirvonen, B. A. Lund, M. W. van der Kamp, P. J. Johnsen, O. Samuelsen, H.-K. S. Leiros

The paper shows that low β-lactam concentrations drive cryptic evolution of β-lactamases through fitness benefits in competition experiments, not increased resistance.

bioRxiv · Dec 1, 2020Evolutionary Biology