Author

J. Aqvist

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Assay:structural biology· 1

Frequent Co-Authors

G. V. Isaksen· 2 shared A. Gogoll· 1 shared A. P. IJzerman· 1 shared A. Söderholm· 1 shared B. A. Lund· 1 shared B. O. Brandsdal· 1 shared D. Andersson· 1 shared E. Sotelo· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersBiochemistry

G. V. Isaksen

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

BiochemistrybioRxivPreprintApr 20, 2023

Biophysical characterization and analysis of a mesophilic chorismate mutase from B. pumilus

R. S. Wilkins, B. A. Lund, G. V. Isaksen…·B. O. Brandsdal

This study reports the first crystal structure and kinetic analysis of a mesophilic chorismate mutase from B. pumilus, using EVB/MD simulations to extract thermodynamic activation parameters.

DOI 10.1101/2023.04.20.537678

bacteria (other)structural biology

𝕏 PostBluesky

BiophysicsbioRxivJun 9, 2021

Deciphering conformational selectivity in the A2A adenosine G protein-coupled receptor by Free Energy simulations

H. Gutierrez de Teran, W. Jespers, L. H. Heitman…·J. Aqvist

This paper uses free energy simulations to study conformational selectivity in the A2A adenosine receptor, revealing how ligands and mutations affect receptor activation and pharmacological profiles.

DOI 10.1371/journal.pcbi.1009152

deep learningstatistical model

𝕏 PostBluesky

BiochemistrybioRxivAug 16, 2020

Structure and mechanism of a phage-encoded SAM lyase revises catalytic function of enzyme family

X. Guo, A. Söderholm, S. Kanchugal P…·M. Selmer

The paper reveals the structure and mechanism of phage-encoded SAM lyases, showing they function as lyases rather than hydrolases, forming MTA and L-homoserine lactone through a unimolecular reaction.

DOI 10.7554/elife.61818

bacteria (other)proteomics

𝕏 PostBluesky