The AMA1-RON complex drives Plasmodium sporozoite invasion in the mosquito and mammalian hosts
P. Fernandes, M. Loubens, R. Le Borgne, C. Marinach, B. Ardin, S. Briquet, L. Vincensini, S. Hamada, B. Hoareau-Coudert, J.-M. Verbavatz, A. Weiner, O. Silvie
This study shows that the AMA1-RON complex is essential for Plasmodium sporozoite invasion of mosquito salivary glands and mammalian hepatocytes, supporting its role in parasite transmission.
bioRxiv · Jan 4, 2022Microbiology