HIV-1 infection reduces NAD capping of host cell snRNA and snoRNA
B. Benoni, J. F. Potuznik, A. Skriba, R. Benoni, J. Trylcova, M. Tulpa, K. Spustova, K. Grab, M.-B. Mititelu, J. Paces, J. Weber, D. Stanek, J. Kowalska, L. Bednarova, Z. Keckesova, , H. Cahova
This study shows HIV-1 infection reduces NAD capping of host snRNA and snoRNA, leading to increased HIV-1 infectivity by destabilizing RNA duplexes.
bioRxiv · Nov 10, 2022Biochemistry