Mitochondria-containing extracellular vesicles from mouse vs. human brain endothelial cells for ischemic stroke therapy
K. M. Dave, V. R. Venna, K. S. Rao, D. B. Stolz, B. Brady, V. A. Quaicoe, M. Maniskas, E. E. Hildebrand, D. Green, M. Chen, J. Milosevic, S.-y. Zheng, S. Shiva, L. D. McCullough, D. S. Manickam
This study compares the therapeutic efficacy of mitochondria-containing extracellular vesicles from mouse and human brain endothelial cells in a mouse stroke model, finding that mouse-derived vesicles are more effective.
bioRxiv · Jan 16, 2024 · PreprintBioengineering