Author

B. C. Richardson

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Cell Biology· 1

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Approach:biophysical modeling· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

B. A. Brownfield· 1 shared J. C. Fromme· 1 shared S. L. Halaby· 1 shared

Activity by Year

2023-2023 · peak 1/yr

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1 shared paperCell Biology

B. A. Brownfield

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1 paper

Recent·Most cited

Cell BiologybioRxivNov 22, 2023

Sec7 regulatory domains scaffold autoinhibited and active conformations

B. A. Brownfield, B. C. Richardson, S. L. Halaby, J. C. Fromme

This study determines the cryoEM structure of autoinhibited Sec7 and proposes an active conformation model based on functional and structural analyses.

DOI 10.1073/pnas.2318615121

cryo-EMexperimental assay