Microbiota colonization tunes the antigen threshold of microbiota-specific T cell activation in the gut
D. Hoces, B. Corak, A. Estrada Brull, S. Berent, E. Faccin, C. Moresi, T. Keys, N. Joller, E. Slack
This study shows that microbiota colonization affects T cell activation thresholds in the gut, with immune system status and TCR specificity influencing responses to colonizing bacteria.
bioRxiv · Jul 29, 2022 · PreprintImmunology