Molecular Dynamics Simulations of Ion Permeation in human NaV Channels
G. Alberini, S. A. Paz, B. Corradi, C. Abrams, F. Benfenati, L. Maragliano
This paper uses molecular dynamics simulations to study ion permeation mechanisms in human Nav channels, revealing distinct single and double Na+ translocation pathways in the selectivity filter.
bioRxiv · Sep 29, 2022Biophysics