Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution
B. Kucukoglu, I. Mohammed, R. C. Guerrero-Ferreira, M. Kube, J. Radecke, S. Ribet, G. Varnavides, M. L. Leidl, K. Lau, S. Nazarov, A. Myasnikov, C. Sachse, K. Mueller-Caspary, C. Ophus, H. Stahlberg
This paper applies low-dose cryo-EM and 4D-STEM ptychography to achieve sub-nanometer resolution 3D reconstructions of frozen hydrated proteins.
bioRxiv · Feb 12, 2024Biophysics