Norepinephrine activates β1-adrenergic receptors localized to the inner nuclear membrane in cortical astrocytes
K. C. Benton, D. S. Wheeler, B. Kurtoglu, M. B. Z. Ansari, D. P. Cibich, D. A. Gonzalez, M. R. Herbst, S. Khursheed, R. C. Knorr, D. Lobner, J. G. Maglasang, K. E. Rohr, A. Taylor, P. J. Witt, P. J. Gasser
This study shows that β1-adrenergic receptors in astrocytes are located in the inner nuclear membrane and respond to norepinephrine via transporter-mediated uptake, activating Gs signaling and PKA.
bioRxiv · Jun 24, 2021Cell Biology