HIV-1 cell-to-cell spread overcomes the virus entry block of non-macrophage-tropic strains in macrophages
M. Han, V. Cantaloube-Ferrieu, M. Xie, M. Armani-Tourret, M. Woottum, J.-C. Pages, P. Colin, B. Lagane, S. Benichou
This study shows that HIV-1 non-macrophage-tropic strains can infect macrophages through cell-to-cell transfer, overcoming entry block limitations seen in cell-free infection.
bioRxiv · Feb 7, 2022Microbiology