Author

T. Lagache

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Animal Behavior & Cognition· 1 Biophysics· 1 Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Assay:electrophysiology· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1

Frequent Co-Authors

J.-C. Olivo-Marin· 3 shared A. Brelot· 1 shared A. C. Dufour· 1 shared A. Desrames· 1 shared A. Imbert· 1 shared A. MALLET· 1 shared A. Saez-Cirion· 1 shared A.-M. Le Sourd· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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3 shared papersCell Biology

J.-C. Olivo-Marin

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Author profile →

4 papers

Recent·Most cited

Single-molecule imaging reveals distinct effects of ligands on CCR5 dynamics depending on its dimerization status

F. Momboisse, G. Nardi, P. Colin, M. Hery, N. Cordeiro, O. Schwartz, N. Sauvonnet, F. Arenzana-Seisdedos, T. Lagache, B. Lagane, J.-C. Olivo-Marin, A. Brelot

This study uses single-molecule imaging to show how different ligands affect CCR5 dynamics based on its dimerization status, revealing distinct effects on receptor mobility and function.

bioRxiv · Dec 20, 2021Cell Biology

HIV-1 hijacks the cell extracellular matrix to spread collectively and efficiently between T lymphocytes

C. Inizan, M. Caillet, A. Desrames, P. Bomme, A. MALLET, K. Bourdic, O. Lambotte, F. Boufassa, M. Mesel-Lemoine, F. Tangy, G. Pancino, H. Mouquet, t. Lagache, A. C. Dufour, J.-C. Olivo-Marin, , M.-I. Thoulouze

This study shows HIV-1 spreads between T lymphocytes via extracellular matrix (ECM)-clustered viral particles, enhancing transmission efficiency and resistance to antiretroviral treatment and antibodies.

bioRxiv · Sep 27, 2021 · PreprintMicrobiology

Electrodiffusion model of synaptic potentials in dendritic spines

T. Lagache, K. Jayant, R. Yuste

The paper models ion concentration dynamics in dendritic spines using electrodiffusion equations and finds that passive diffusion, spine geometry, and spine-neck resistance shape synaptic potentials.

bioRxiv · Aug 1, 2018Biophysics

Live Mouse Tracker: real-time behavioral analysis of groups of mice

F. de Chaumont, E. Ey, N. Torquet, T. Lagache, S. Dallongeville, A. Imbert, T. Legou, A.-M. Le Sourd, P. Faure, T. Bourgeron, J.-C. Olivo-Marin

The paper introduces a real-time behavioral analysis system for group-housed mice using computer vision and RFID, revealing distinct behavioral traits in Shank2 and Shank3 mutant mice.

bioRxiv · Jun 18, 2018Animal Behavior & Cognition