Author

B. Lechat

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Sablina· 1 shared E. Stites· 1 shared E. Van Boxel· 1 shared G. Vande Velde· 1 shared P. Zhao· 1 shared R. Sewduth· 1 shared T. Ivanisevic· 1 shared W. Magits· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 36 mutual co-author links

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1 shared paperCancer Biology

A. Sablina

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1 paper

Recent·Most cited

Increased dosage of wild-type KRAS protein drives KRAS-mutant lung tumorigenesis and drug resistance

T. Ivanisevic, W. Magits, Y. Ma, P. Zhao, E. Van Boxel, B. Lechat, E. Stites, G. Vande Velde, R. Sewduth, A. Sablina

This study shows that increased wild-type KRAS protein dosage in KRAS-mutant lung cancer drives tumor growth and drug resistance, with vascular changes mediated by mTOR pathway activation.

bioRxiv · Feb 27, 2024 · PreprintCancer Biology