Author

B. Liau

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:CRISPR screen· 1 Assay:DNA methylation· 1

Frequent Co-Authors

A. L. Waterbury· 1 shared A. M. Freedy· 1 shared A. P. Siegenfeld· 1 shared D. D. Hwang· 1 shared E. M. Garcia· 1 shared H. S. Kwok· 1 shared J. K. Liang· 1 shared J. W. Morriss· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCancer Biology

A. L. Waterbury

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2 papers

Recent·Most cited

Base Editor Scanning Reveals Activating Mutations of DNMT3A

E. M. Garcia, N. Z. Lue, J. K. Liang, W. K. Lieberman, D. D. Hwang, J. Woods, B. Liau

The paper uses base editor mutagenesis to identify activating DNMT3A mutations, revealing hyperactivating variants in the ADD domain that remain functional in the presence of a heterozygous R882H mutation.

bioRxiv · Apr 12, 2023Biochemistry

Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma

H. S. Kwok, A. M. Freedy, A. P. Siegenfeld, J. W. Morriss, A. L. Waterbury, S. M. Kissler, B. Liau

The paper identifies drug addiction mutations in EZH2-mutant lymphoma that reveal a methylation ceiling, showing how inhibiting SETD2 can block lymphoma growth.

bioRxiv · Apr 4, 2022Cancer Biology