Cancer BiologybioRxiv
Drug addiction mutations unveil a methylation ceiling in EZH2-mutant lymphoma
H. S. Kwok, A. M. Freedy, A. P. Siegenfeld…·B. Liau
The paper identifies drug addiction mutations in EZH2-mutant lymphoma that reveal a methylation ceiling, showing how inhibiting SETD2 can block lymphoma growth.
DOI 10.1038/s41589-023-01299-1