The Oncogenic Function of PLAGL2 is Mediated via Specific Target Genes Through a Wnt-independent Mechanism in Colorectal Cancer
A. Fischer, D. Veronese-Paniagua, S. Swaminathan, H. Kashima, D. C. Rubin, B. Madison
This study identifies PLAGL2 as a key driver of colorectal cancer by promoting proliferation and cell cycle progression through direct target genes IGF2 and ASCL2, independent of Wnt signaling.
bioRxiv · Oct 14, 2020 · PreprintCancer Biology