Structural features of Dnase1L3 responsible for serum antigen clearance
J. J. McCord, M. Engavale, E. Masoumzadeh, J. Villarreal, B. Mapp, M. P. Latham, P. A. Keyel, R. B. Sutton
This study identifies structural features of Dnase1L3 that enable its unique ability to degrade antigenic DNA complexes, preventing autoimmunity.
bioRxiv · Jan 19, 2022Biochemistry