Author

B. Ortiz

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Cell Biology· 1

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Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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J. A. Klickstein· 1 shared M. Raman· 1 shared P. Juo· 1 shared S. Mukkavalli· 1 shared

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2020-2020 · peak 1/yr

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1 shared paperCell Biology

J. A. Klickstein

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1 paper

Recent·Most cited

The p97-UBXN1 complex regulates aggresome formation

S. Mukkavalli, J. A. Klickstein, B. Ortiz, P. Juo, M. Raman

This study shows that the p97-UBXN1 complex is essential for aggresome formation and clearance, with UBXN1 specifically required for proper aggresome assembly and reduced polyQ aggregate formation in Huntington's disease models.

bioRxiv · Sep 3, 2020Cell Biology