B. Sahu

Cancer cell type-specific derepression of transposable elements by inhibition of chromatin modifier enzymes

The paper investigates how inhibiting chromatin modifier enzymes in cancer cells leads to cell-type-specific derepression of transposable elements, enhancing immune response through distinct mechanisms.

Direct conversion of human fibroblasts to pancreatic epithelial cells through transient progenitor states is controlled by temporal activation of defined factors

This study reprograms human fibroblasts to pancreatic exocrine cells using six transcription factors and identifies transient progenitor states as key intermediates in the process.

Lineage-specific oncogenes drive growth of major forms of human cancer using common downstream mechanisms

The paper identifies common downstream mechanisms driven by lineage-specific oncogenes that regulate cell proliferation in various cancers.