Palmitoyl transferase ZDHHC20 promotes pancreatic cancer metastasis
G. Tomic, C. Sheridan, A. Y. Refermat, M. P. Baggelaar, J. Sipthorp, B. Sudarshan, C. A. Ocasio, A. Suarez-Bonnet, S. L. Priestnall, E. Herbert, E. W. Tate, J. Downward
This study identifies ZDHHC20 as a palmitoyl transferase promoting pancreatic cancer metastasis by affecting tumor-immune interactions, with no effect on proliferation or primary tumor growth.
bioRxiv · Feb 8, 2023Cancer Biology