Nucleotidyltransferase toxin MenT targets and extends the aminoacyl acceptor ends of serine tRNAs in vivo to control Mycobacterium tuberculosis growth
X. XU, R. BARRIOT, B. VOISIN, T. J. ARROWSMITH, B. USHER, C. GUTIERREZ, X. HAN, P. REDDER, T. R. BLOWER, O. NEYROLLES, P. GENEVAUX
This study identifies MenT3 as a tRNA nucleotidyltransferase that modifies serine tRNAs in Mycobacterium tuberculosis, affecting bacterial growth and revealing its role in infection.
bioRxiv · Mar 7, 2024Microbiology