Caught in the Act: targeted mutagenesis of the herpesvirus fusogen central helix captures transition states
M. Zhou, B. Vollmer, E. Machala, M. Chen, K. Grünewald, A. M. Arvin, W. Chiu, S. L. Oliver
This study mutates the herpesvirus fusogen gB to capture its transition state, revealing the critical role of domain III in membrane fusion.
bioRxiv · Nov 23, 2022 · PreprintMicrobiology