In situ single-cell CRISPR screens uncover context-dependent rewiring of glioma states and immune recruitment
Nicholas Hou, Ioana-Teodora Lia, Ross M Giglio, Bailey T Van, Sebastian Pallais-Aks, Mathini Vaikunthan, Vivian Lu, Jonathan Guo, Destinee Williams, Tiffany Camila Nieto, Lingting Shi, Cody Slater, Elham Azizi, Jose L McFaline-Figueroa
The paper uses in vivo single-cell CRISPR screens to study how tumor suppressor loss and genetic perturbations affect glioma states and immune recruitment in mice.
bioRxiv · Nov 10, 2026 · PreprintGenomics