Assessment of Neurovascular Coupling & Cortical Spreading Depression in Mixed Models of Atherosclerosis & Alzheimer's Disease
Osman Shabir, Ben Pendry, Llywelyn Lee, Beth Eyre, Paul S. Sharp, Monica A Rebollar, David Drew, Clare Howarth, Paul Roy Heath, Stephen B. Wharton, Sheila Francis, Jason Berwick
This study assesses neurovascular coupling and cortical spreading depression in models of atherosclerosis and Alzheimer's disease, finding exacerbated neurovascular decline and increased amyloid-beta plaques in comorbid conditions.
eLife · Dec 20, 2021Peer-reviewedNeuroscience