Author

Benedikt Bauer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Evolutionary Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:deep learning· 2 Approach:statistical model· 2 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Adriana BadarauiD· 2 shared Andrea Majoros-Hashempour· 2 shared Donaat KestemontiD· 2 shared Julia Schmidt· 2 shared Lorenzo CorsiniiD· 2 shared Manuel Zerbs· 2 shared Marina von Freyberg· 2 shared Renping QiaoiD· 2 shared

Activity by Year

2015-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBioengineering

Adriana BadarauORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

A chimeric, half-life extended lysin with a unique mode of action

Zehra Visram, Donaat Kestemont, Benedikt Bauer, Renping Qiao, Svetlana Ðurica-Mitić, Andrea Majoros-Hashempour, Julia Schmidt, Rocío Berdaguer, Karsten Krey, Michele Mutti, Manuel Zerbs, Marina von Freyberg, Lorenzo Corsini, Adriana Badarau

This paper develops a half-life extended lysin by fusing it to an Fc fragment, showing improved efficacy against staphylococcal infections through targeted release.

Frontiers in Microbiology · Aug 21, 2026Peer-reviewedBioengineering

Multi-dimensional optimization of a lysin towards a ribolysin against life-threatening S. aureus infections: Fc-LysM-CHAP and its strong synergy with standard of care antibiotics

Adriana Badarau, Benedikt Bauer, Zehra Visram, Renping Qiao, Andrea Majoros-Hashempour, Johannes Söllner, Svetlana Ðurica-Mitić, Orla M. Dunne, Robert Kluj, Donaat Kestemont, Ann-Katrin Kieninger, Monika Kulig, Rocío Berdaguer, Timo Schwebs, Manuel Zerbs, , Lorenzo Corsini

This paper develops an Fc-fused lysin, Fc-LysM-CHAP, optimized for improved pharmacokinetics and synergy with antibiotics against S. aureus infections.

bioRxiv · May 8, 2026 · PreprintMicrobiology

Toxicity Management in CAR T cell therapy for B-ALL: Mathematical modelling as a new avenue for improvement.

Shalla Hanson, David Robert Grimes, Jake P. Taylor-King, Benedikt Bauer, Pravnam I. Warman, Ziv Frankenstein, Artem Kaznatcheev, Michael J. Bonassar, Vincent L. Cannataro, Zeinab Y. Motawe, Ernesto A. B. F. Lima, Sungjune Kim, Marco L. Davila, Arturo Araujo

This paper develops a mathematical model to explore toxicity in CAR T cell therapy for B-ALL, finding that initial tumour burden is a stronger predictor of toxicity than CAR T cell dose.

bioRxiv · Apr 22, 2016 · PreprintCancer Biology

Repeatability of evolution on epistatic landscapes

Benedikt Bauer, Chaitanya S Gokhale

This study investigates mutational path probabilities in systems with epistatic effects on fitness and mutation rates, showing that pathways previously negligible can become accessible under varying conditions.

bioRxiv · Mar 20, 2015Evolutionary Biology