Cardiomyocyte caveolae govern myocardial function and sex-dependent regulation of ventricular compliance and resilience via cavin-1
Benjamin T Quick, H. Khoo, Tayla Bishop, JS Russell, Sidney Niogret, Jennifer E. Outhwaite, Uda Y. Ho, Liam J Griffiths, Zunhan Lu, James A. Rae, Nathan J. Palpant, Robert G. Parton, Walter G. Thomas, John Patrick Headrick, Melissa E. Reichelt
This study investigates the role of cardiomyocyte caveolae and cavin-1 in myocardial function, revealing sex-dependent effects on ventricular compliance and resilience through mechanisms involving NOS signaling and fibrosis.
bioRxiv · Apr 21, 2026 · PreprintPhysiology