Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages
Els Wauters, Pierre Van Mol, Abhishek D. Garg, Sander Jansen, Yannick Van Herck, Lore Vanderbeke, Ayse Bassez, Bram Boeckx, Bert Malengier-Devlies, Anna Timmerman, Thomas Van Brussel, Tina Van Buyten, Rogier Schepers, Elisabeth Heylen, Dieter Dauwe, , Diether Lambrechts
This study uses single-cell profiling of bronchoalveolar lavages to compare immune responses in mild and critical COVID-19, identifying differences in T-cell function and macrophage differentiation that correlate with disease severity.
bioRxiv · Jul 9, 2020Immunology