Author

Johan Neyts

Primary ORCID profile (0000-0002-0033-7514 · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Johan NeytsiD1 paper

Biology Disciplines

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Microbiology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1

Frequent Co-Authors

Bert Malengier-Devlies· 2 shared Patrick Matthys· 2 shared Sander Jansen· 2 shared Abhishek D. Garg· 1 shared Anna Timmerman· 1 shared Ayse Bassez· 1 shared Birgit WeynandiD· 1 shared Bram BoeckxiD· 1 shared

Activity by Year

2016-2020 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersImmunology

Bert Malengier-Devlies

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3 papers

Recent·Most cited

Discriminating Mild from Critical COVID-19 by Innate and Adaptive Immune Single-cell Profiling of Bronchoalveolar Lavages

Els Wauters, Pierre Van Mol, Abhishek D. Garg, Sander Jansen, Yannick Van Herck, Lore Vanderbeke, Ayse Bassez, Bram Boeckx, Bert Malengier-Devlies, Anna Timmerman, Thomas Van Brussel, Tina Van Buyten, Rogier Schepers, Elisabeth Heylen, Dieter Dauwe, , Diether Lambrechts

This study uses single-cell profiling of bronchoalveolar lavages to compare immune responses in mild and critical COVID-19, identifying differences in T-cell function and macrophage differentiation that correlate with disease severity.

bioRxiv · Jul 9, 2020Immunology

A single-dose live-attenuated YF17D-vectored SARS-CoV2 vaccine candidate

Lorena Sanchez Felipe, Thomas Vercruysse, Sapna Sharma, Ji Ma, Viktor Lemmens, Dominique van Looveren, Mahadesh Prasad Arkalagud Javarappa, Robbert Boudewijns, Bert Malengier-Devlies, Suzanne F. Kaptein, Laurens Liesenborghs, Carolien De Keyzer, Lindsey Bervoets, Madina Rasulova, Laura Seldeslachts, , Kai D

This paper develops a single-dose YF17D-vectored SARS-CoV-2 vaccine candidate that induces neutralizing antibodies and protects against infection in hamsters.

bioRxiv · Jul 8, 2020 · PreprintMicrobiology

The viral polymerase inhibitor 7-deaza-2’-C-methyladenosine is a potent inhibitor of in vitro Zika virus replication and delays disease progression in a robust mouse infection model

Joanna Zmurko, Rafael E Marques, Dominique Schols, Erik Verbeken, Suzanne J.F. Kaptein, Johan Neyts

The paper identifies 7DMA as a potent ZIKV inhibitor through in vitro assays and validates its efficacy in a mouse model, delaying disease progression.

bioRxiv · Mar 1, 2016Microbiology