Epigenetic modulation of NLRP6 inflammasome sensor as a therapeutic modality to reduce necroptosis-driven gastrointestinal mucosal dysfunction in HIV/SIV infection
Lakmini S. Premadasa, Marina McDew‐White, Luis Romero, Beverly Gondo, Jade A. Drawec, Binhua Ling, Chioma M. Okeoma, Mahesh Mohan
This study shows that epigenetic modulation of NLRP6 reduces necroptosis and gastrointestinal inflammation in HIV/SIV-infected rhesus macaques.
Cell Communication and Signaling · Apr 25, 2025Peer-reviewedPathology