Author

Bianca Ruppert

Heidelberg University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:development & morphogenesis· 1 Organism:mouse· 1 Organism:yeast· 1

Frequent Co-Authors

Axel C. R. DiernfellneriD· 3 shared Michael BrunneriD· 3 shared Fidel Emmanuel SerranoiD· 2 shared Carolin SchunkeiD· 1 shared Daniela MarzolliD· 1 shared Sabine Schultz· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

6 top collaborators · 11 mutual co-author links

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3 shared papersBiochemistry

Axel C. R. DiernfellnerORCID

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3 papers

Recent·Most cited

Cell cycle-coupled CK1δ turnover, autoinhibition, and activity

Fidel Emmanuel Serrano, Bianca Ruppert, Axel C. R. Diernfellner, Michael Brunner

This study shows CK1δ activity and abundance are coordinated in a cell cycle-dependent manner, with degradation and autoinhibition playing roles in different phases.

bioRxiv · Aug 26, 2026 · PreprintBiochemistry

Nuclear CK1δ as a Critical Determinant of PER:CRY Complex Dynamics and Circadian Period

Fidel Emmanuel Serrano, Daniela Marzoll, Bianca Ruppert, Axel C. R. Diernfellner, Michael Brunner

This study investigates the role of nuclear CK1δ in PER:CRY complex dynamics and circadian period regulation, showing its impact on complex formation and nuclear clearance of PER2.

eLife · Jun 15, 2026Peer-reviewedBiochemistry

CK1a-Mediated Two-Step Subunit Remodeling of the Circadian FRQ-FRH Complex

Carolin Schunke, Bianca Ruppert, Sabine Schultz, Axel C. R. Diernfellner, Michael Brunner

The paper reveals how CK1a-mediated phosphorylation of FRQ leads to a two-step remodeling of the FRQ-FRH complex, enabling precise circadian regulation through temporal decoding of phosphorylation states.

bioRxiv · May 13, 2025 · PreprintCell Biology