An ultrasensitive method for detecting mutations from short and rare cell-free DNA
Lin Wang, Yu Zhuang, Yue Yu, Zhiwei Guo, Qiaomei Guo, Lihua Qiao, Xueqing Wang, Xiaohui Liang, Pengpeng Zhang, Qifan Li, Chenjun Huang, Rong Cong, Yinghui Li, Bin Che, Huihui Xiong, , Jiatao Lou
This paper introduces OPERA, a method for detecting low-frequency mutations in short and rare cell-free DNA, achieving higher sensitivity than existing methods.
Biosensors and Bioelectronics · Oct 1, 2023Peer-reviewedGenetic & Genomic Medicine