Pengpeng Zhang

THER is a web tool that integrates hypoxia-related transcriptomic data to analyze tumor hypoxia mechanisms and drug responses.

The paper develops the AGAE score, a pan-cancer biomarker for predicting immune checkpoint inhibitor response, showing improved predictive power over existing biomarkers and identifying CEP55 as a key target for immunotherapy.

This paper introduces OPERA, a method for detecting low-frequency mutations in short and rare cell-free DNA, achieving higher sensitivity than existing methods.