Author

Bin Yan

University of Hong Kong

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Bioinformatics· 2 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:deep learning· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1

Frequent Co-Authors

Junwen Wang· 2 shared Cheng Li· 1 shared Chuiyan Ma· 1 shared Dan Jiang· 1 shared Dan YuiD· 1 shared Evelyn Yilin Wang· 1 shared Hong Feng· 1 shared Hung-Fat Tse· 1 shared

Activity by Year

2018-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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2 shared papersBioinformatics

Junwen Wang

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4 papers

Recent·Most cited

Multi-model biological and sequence information fusion for gene regulatory network inference from single-cell transcriptomics

lin zhong, Bin Yan, Junwen Wang, minzhu xie

This paper introduces scMGFGRN, a deep learning framework for gene regulatory network inference from single-cell transcriptomics, which outperforms existing methods by integrating multimodal biological data.

bioRxiv · Sep 19, 2026 · PreprintBioinformatics

Integrative Multi-Omics Analysis Identifies a Functional Enhancer Driving Tumorigenesis in Head and Neck Squamous Cell Carcinoma

Pengfei Xu, Xiaorong Liu, Jane Jingya Pu, Xiaoling Lu, Victor Ho-Fun Lee, Evelyn Yilin Wang, Qianhui Jiang, Dan Yu, Bin Yan, Jinlin Song, Qi Zhong, Ping Yang, Nhan L. Tran, Xinyuan Guan, Yu-Xiong Su, Junwen Wang

The paper identifies a functional enhancer, GH05J001312, that drives tumorigenesis in HNSCC by enhancing TERT expression and affecting cancer-related pathways.

bioRxiv · Feb 5, 2026 · PreprintCancer Biology

A gene co-expression network-based analysis of mesenchymal stromal cells reveals novel genes and molecular pathways underlying heterotopic ossification

Meiling Yang, Yongpeng Shi, Shichao Shen, Bin Yan, Lei Yang, Liuxun Li

The paper identifies HO-related gene modules and hub genes using WGCNA and PPI networks, revealing pathways involved in stem cell pluripotency and immune responses.

bioRxiv · Dec 1, 2024 · PreprintBioinformatics

Mesenchymal stem cells protect retinal ganglion cells from degeneration via mitochondrial donation

Dan Jiang, Hong Feng, Zhao Zhang, Bin Yan, Ling Chen, Chuiyan Ma, Cheng Li, Shuo Han, Yuelin Zhang, Peikai Chen, Hung-Fat Tse, Qingling Fu, Kin Chiu, Qizhou Lian

This study shows that mesenchymal stem cells (MSCs) protect retinal ganglion cells (RGCs) from degeneration by donating mitochondria, reducing inflammation, and preserving retinal function in a mouse model.

bioRxiv · Aug 19, 2018 · PreprintCell Biology