Intrauterine Growth-Restricted Pregnant Rats, from Hypertensive Placental Ischemic Dams Display Preeclamptic-like Symptoms: A New Rodent Model of Preeclampsia
Jonna Smith, Madison Powell, Whitney Cromartie, Savanna Smith, Kylie Jones, Angie Castillo, Jordan Shaw, Joseph Editone, Ahfiya Howard-Cunningham, Robert Tatum, A. N. Smith, Brandon Fisher, George W. Booz, M. W. CUNNINGHAM
This study establishes a new rodent model of preeclampsia by inducing intrauterine growth restriction in pregnant rats, showing elevated blood pressure and oxidative stress.
bioRxiv · Feb 7, 2024 · PreprintPhysiology