Infection Of Rhesus Macaques With Onyong-nyong Virus UVIR-O804 Recapitulates Key Aspects of Human Clinical Disease
Hannah K. Jaeger, Michael C. Denton, Takeshi F. Andoh, Craig N. Kreklywich, Lina Gao, Lydia J. Pung, Zachary J. Streblow, Ann McMonigal, Karina Ray, Brayden Graves, Magdalene M. Streblow, Aaron M. Barber-Axthelm, Gavin Zilverberg, Margaret Terry, Suzanne S. Fei, , Daniel N. Streblow
This study infects rhesus macaques with a recent ONNV clinical isolate, demonstrating viremia, immune activation, and clinical disease features similar to human infection.
bioRxiv · Nov 20, 2025 · PreprintMicrobiology